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Studies consistently show that smoking has an important impact on the incidence of UC (16, Salmonella , Shigella , and Campylobacte r motive adjustments in the intestine microbiota, which can additionally be considered in the use of antibiotics to deal with these prerequisites ( 2.2.2 Individual differences and inheritance It is estimated that 11.6 out of every 100,000 Chinese suffer from UC, according to a large number of statistical studies, especially in the southeastern coastal areas with Westernized lifestyles, North America and Europe have higher rates of UC than Asia, with 156 to 291 cases per 100,000 people ( 2.2.3 Dysregulation of the immune response Researchers have found that UC results in a balance to be upset between the antigen-presenting cells, the helper T cells, the regulatory T cells, and the natural killer T cells