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314,315,316 An increase in peroxisome proliferator activated receptor gamma 2 (PPAR2) and upregulation of hippocampal catalase in KD-fed rats are observed, which may increase anti-inflammatory and antioxidant activity

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Body Composition: Individuals with different body compositions, particularly those with higher body fat percentages, may experience a slower onset of effects because semaglutide GLP-1 interacts differently in the body

For steady-state BE studies (if applicable): AUC and Cmax: 90% CI within 80.00125.00% Cmin: Test product must not be less than 80% of reference