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doi: 10.1128/mbio.00842-22 41 CallegariS.McKinnonR
Constipation may also prolong contact with biliary metabolites and allow more deconjugation and reabsorption
If your whole body is toxic, yeah, because theres a blood brain barrier that you cannot cross, so the toxicity ranges in the brain is reduced by dramatically because the body cannot reach there
Fetal Diagn Ther
Every functional endpoint in the Baar paper was read at roughly this point, not earlier: running-wheel activity was scored 18 to 21 days after the first dose, and plasma urea, creatinine, fur density and responsiveness at day 30
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