Most trials that produced the headline numbers enrolled patients who already had the disease being studied
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Kidney function: In some cases, tirzepatide may affect kidney function
What's new: Research on NAD+ precursors (NMN, NR) continues to show improved insulin sensitivity and reduced metabolic dysfunction in animal models
Biologics License Application (BLA), not NDA: Retatrutide is regulated as a biologic, so Lilly will file a BLA rather than a small-molecule NDA
[36] Vitamin B 12 deficiency is most commonly caused by malabsorption, but can also result from low intake, immune gastritis, low presence of binding proteins, or use of certain medications