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By comparing gene expression patterns between recurrent and non-recurrent cases across these two time points, we sought to determine whether key resistance-related molecular programs are primarily induced during NAC or are already detectable prior to treatment

PI3K/AKT/mTOR signaling transduction pathway and targeted therapies in cancer

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Naturally Elevated IGF-1 Levels IGF-1 is the main downstream mediator of GH effects, responsible for anabolism, muscle growth, and tissue repair