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Whereas it is unlikely that the topical preparation as such immediately and directly reaches the hair bulb region, it has been shown that drug delivery to the skin occurs also through the hair follicles [32]
"Thats why these taste shifts are often more pronounced early on, and tend to settle once the patients weight stabilises." Other theories include the presence of GLP-1 receptors in taste buds themselves, which may alter how we process flavour, and the slowing of digestion, which can make foods feel heavier and affect how theyre perceived in the mouth
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Oral drugs do away with several of the drawbacks that are associated with injectable drugs, such as needle fear and difficulties with administration
