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Categorical data were described using frequencies and percentages, and differences between groups were analyzed using the chi-square test or Fishers exact test

This includes common abbreviations and marketing names

In an experiment from a single representative donor, antagonizing the GLP-1R failed to reduce tirzepatide-stimulated insulin secretion, whereas antagonizing the GIPR reduced insulin secretion by ~55% (Fig

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Beyond that, the evidence is per-compound plus the CagriSema (cag + sema) Phase 3 data as the closest human analog