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When muscle drops too much during weight loss, patients may experience: Reduced strength Lower energy Poorer exercise tolerance Increased frailty risk Greater chance of weight regain Less favorable body shape after weight loss Reduced metabolic flexibility Higher risk of functional decline with aging This is one reason the term skinny fat has become common in wellness conversations

Summary: Combining Januvia (sitagliptin) and Rybelsus (semaglutide) is generally not recommended in the UK due to limited additional benefit and poor cost-effectiveness

FAQ Melissa Sleight, RDN Medical Reviewer Jessica Migala Author Jessica Migala is a freelance writer with over 15 years of experience, specializing in health, nutrition, fitness, and beauty

That is what I was talking about

For studies that were over one year in duration, this increased to 8 kilograms

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