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The breadth of documented activity reflects what the original investigators have described as systems-level pharmacology: rather than acting through a single high-affinity receptor, BPC-157 appears to modulate multiple intersecting cellular pathways including nitric oxide signalling, growth-factor receptor expression, dopamine and serotonin metabolism, and angiogenic vessel formation

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de Oliveira Santana KN, Lelis DF, Mendes KL, Lula JF, Paraiso AF, et al

doi: 10.1113/jphysiol.2004.063388 106 ClarkeGGrenhamSScullyPFitzgeraldPMoloneyRShanahanFet al