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Bee venom and its peptide component melittin suppress growth and migration of melanoma cells via inhibition of PI3K/AKT/mTOR and MAPK pathways
These vesicles, typically 30150 nm in diameter, are composed of lipids, proteins, nucleic acids, and other signaling molecules, and can be engineered to carry therapeutic agents such as drugs, peptides, or RNA
Journal of Applied Physiology , 82, 571-576
The key is to use the lowest effective volume and frequency to correct the deficiency or meet the metabolic need, and to adjust as the patients condition improves
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