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Materials and Methods Reagents Liraglutide was provided by Novo Nordisk (Bagsvaerd, Denmark)

Standard cycle: 46 weeks Extended cycle with monitoring: up to 12 weeks for complex or chronic presentations Rest period between cycles: 48 weeks is typical Duration matters because tissue remodeling continues for weeks after a cycle ends

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GP, GL, VC, and VL contributed to the clinical follow-up of patients

Individuals with type 2 diabetes may experience more pronounced first-month weight loss due to improved glycemic control, which reduces water retention and metabolic inflammation