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Medicaid Spending on GLP-1 Drugs by State Data Source: IRIS by Real Chemistry | Image Credit: Real Chemistry Nationally, Medicaid spending on GLP-1s totaled $3.5 billion between November 2023 and October 2024, averaging $48 per Medicaid enrollee

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In one study, microdosing GLP-1s supported moderate weight loss of up to 10 pounds over 40 weeks in participants. MICRODOSING GLP-1 BENEFITS Do More, Age Less Modulated inflammatory pathways in clinical trials. Studies found a reduced risk of cognitive decline Supported cardiovascular health in clinical trials Improved mitochondrial function and oxidative stress in clinical trials Low doses reduced side effects in clinical trials Supported moderate weight loss of up to 10 pounds over 40 weeks in one study *See studies cited below

Ethics declarations Ethics approval All procedures, protocols, and medications were approved by the Johns Hopkins University Animal Care and Use Committee and were performed in accordance with the Association for Research in Vision and Ophthalmology statement for use of animals in ophthalmic and vision research, and the National Institutes of Health guide for the care and use of laboratory animals