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doi: 10.1007/s00284-017-1256-4
Substantial weight loss was achieved: Up to 20% bodyweight reduction was seen in the highest dose of tirzepatide compared with placebo
Moreover, genes found to be induced by TGF in diverse studies were down-regulated in regions of severe emphysema
Important safety information: Zepbound has a boxed warning for risk of thyroid C-cell tumors and is contraindicated in patients with a personal or family history of medullary thyroid carcinoma (MTC) or in patients with Multiple Endocrine Neoplasia syndrome type 2 (MEN 2)
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