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The TH mimics-induced improvement in glucose homeostasis was usually considered to be secondary to weight loss 17

The IGF-1 stimulation, glucose effects, and growth-promoting properties come from a different region of HGH

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Bile acids induce GLP-1 secretion in mice via activation of the basolateral TGR5 receptor in enteroendocrine L-cells

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Research suggests that GLP-1 medications may help counteract some of these responses