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Although the mechanism of acetaminophen toxicity is well recognized, the clinical implications of age-related differences and the ontogeny of hepatic pathways may not be commonly appreciated

Before performing docking experiments, we utilized the PSN-ENM method to gain a comprehensive understanding of the distinct characteristics and similarities between MRP1 and MRP7 and to reveal the unique binding modes of these two proteins

These disruptions lead to excessive lipid ROS accumulation, resulting in cellular damage and matrix degradation

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Targeting GSTP1-1 induces JNK activation and leads to apoptosis in cisplatin-sensitive and -resistant human osteosarcoma cell lines

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