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Semaglutide triggers weight loss by slowing stomach emptying and signaling fullness to the brainbut this same mechanism can cause diarrhea in the first 48 weeks of treatment
These medications mimic the bodys natural glucagon-like peptide-1 (GLP-1) hormone, which slows digestion, reduces hunger, and supports insulin regulation
Additionally, the phrase needle-free GLP-1 is especially appealing for those who are afraid of needles
Moreover, adverse effects such as nasal irritation and epistaxis (nosebleeds) can further discourage patients from adhering to their treatment plans [5]
What happens to side effects if you stop and restart semaglutide If you stop semaglutide for any reason, whether due to surgery, supply issues, or personal choice, restarting semaglutide requires going through the dose escalation process again
There is no absolute contraindication to using these medicines together, and no official pharmacological interaction has been documented that would prevent their concurrent use
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