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Researchers sometimes study CJC-1295 alone, Ipamorelin alone, or alternative secretagogues like MK-677 as standalone compounds

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At 24 months, 17.8 kg reduction from baseline (99.5 kg to 81.7 kg), BMI reduced by 5.5 kg/m (from 36.5 to 31.0 kg/m), maintaining 20.6% 3.2% weight loss, though 95% attrition limits clinical interpretability