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There is currently no specific treatment available for this disease
000 genetic markers
affected puppies exhibit stereotypical positioning of limbs
In Australian Shepherds the disease was identified between 4 and 19 months of age
three or four single copy variants of bc
A-Lokus Labrador Retriever There is currently no specificAgouti signal peptide (ASIP) or A Locus is responsible for many different colour patterns in dogs. Specific A Locus allele products can interact with functional MC1R and thus interfere with production of black melanin. Dogs have four different ASIP gene alleles with following dominance hierarchy: Ay > aw > at > a, meaning that the most dominant allele present will be expressed. Genes on A Locus (agouti) are expressed only if a dog on K Locus does not
