Vitamin D-abhängige Rachitis, Typ IA Einzelanalyse The dilution of black pigment

The dilution of black pigment results in blue or grey coat colour

generalized muscle atrophy and cardiomyopathy is observed in the English Springer Spaniels

which is described as the canine moustache and eyebrows

The condition is caused by complete absence of fibrinogen

Mutation: AGXT gene

Vitamin D-abhängige Rachitis, Typ IA Einzelanalyse The dilution of black pigmentVitamin D deficiency rickets, type IA is an autosomal recessive disorder of bone development in young, growing dogs because of deficiency of vitamin D. The resultant active form of vitamin D is a steroid hormone that plays a vital role in whole body calcium homeostasis. The clinical signs of rickets arise from low serum calcium, failure of calcification of bones, leading to bone deformities, such as bowing of limbs, delayed dentition, lameness and