Angeborene Augenfehlbildung (CEM) Labrador Retriever Mutation: ACADM gene

Mutation: ACADM gene

DCM4 clear

moxidectin

Reduced hair shedding (MC5R) is a complex genetic trait that can affect all breeds and has epistatic interactions with FGF5 (coat length) and RSPO2 (furnishing)

If the parent animals have an ISAG2020 profile

Angeborene Augenfehlbildung (CEM) Labrador Retriever Mutation: ACADM geneEye Malformations can be caused by environmental or genetic factors. A new form of CEM has been observed in Golden Retrievers with clinical signs including unilateral or bilateral retina dysplasia and or optic nerve hypoplasia. In some severe cases, dogs are euthanized due to bilateral changes, aggressivity, or some other severe clinical signs. A mutation in SIX6 gene has been observed in Golden Retrievers with CEM, suggesting a strong connection