Leukozyten Adhäsionsdefizienz Typ III (LAD3) Katzen bei denen langhaarige Hunde (auch

bei denen langhaarige Hunde (auch 'fluffies' genannt) gemäß dem Rassestandard nicht erlaubt sind

Clinical signs in Leonberger vary greatly and have different age of onset from <1 year to 10 years of age

agouti coat patterns are not expressed due to dominant KB allele

It causes a cytoplasmic accumulation of granular material within cerebellar cells

einschließlich des Old English Sheepdog

Leukozyten Adhäsionsdefizienz Typ III (LAD3) Katzen bei denen langhaarige Hunde (auchLeukocyte adhesion deficiency (LAD3) is a rare canine autosomal recessive disorder characterised by failure of activation of beta 13 type integrins, expressed on haematopoietic cells. That results in bleeding diathesis, while leukocyte count remains normal. The symptoms start to show at around 6 months of age and include abnormal bleeding, dental disease, pyrexia, lameness and infections, such as deep pyoderma, pododermatitis, gingivitis and