Lethale Akrodermatitis (LAD) All muscles and skin

muscles and skin

The disease was first identified in Shetland sheepdogs

Inheritance: autosomal dominant (incomplete penetrance)

CMR1 is found in different dog breeds

Die betroffenen Welpen müssen oft aufgrund schwerer Symptome eingeschläfert werden

Lethale Akrodermatitis (LAD) All muscles and skinLethal acrodermatitis (LAD) is characterized by poor growth, immune deficiency, and skin lesions, especially at the paws. Affected puppies show characteristic skin lesions on the feet and on the face, diarrhoea, bronchopneumonia, and a failure to thrive. Coat color can be diluted in pigmented skin areas. LAD affected dogs are immunodeficient and frequently suffer from skin infections with Malassezia or Candida. They grow slower than their non affected