Progressive Retinaatrophie, X-chromosomal 1 (XLPRA) CatCheck Affected dogs cannot be used

Affected dogs cannot be used for hunting as they collapse and develop tetraparesis or tetraplegia shortly after exercise

Mutation: BBS2 gene

The disease leads to crusts and fissures on the nasal pad of Labrador Retrievers

rupture of bladder and death

meanwhile the neurological abnormalities are likely to be present much earlier

Progressive Retinaatrophie, X-chromosomal 1 (XLPRA) CatCheck Affected dogs cannot be usedProgressive retinal atrophy (PRA) in dogs is a group of genetically heterogeneous inherited retinal disorders characterized by progressive degeneration and cell death of photoreceptors. X linked progressive retinal atrophy (XL PRA) is an X linked form of retinitis pigmentosa. Affected dogs have normal retina at birth. The first clinical symptoms appear at 6 months. Rod light receptors begin to appear irregularly damaged, later cone damage arises, and