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When breeding with merle dogs
Coat color and coat characteristics
Mutation: PLN gene
Mutation: COLQ gene
Bei gesunden Hunden wird L-2-Hydroxyglutarat zu 2-Oxoglutarat (Alpha-Ketoglutarat) metabolisiert
Progressive Retinaatrophie, Cone-Rod Dystrophie 1 (American Pit Bull Terrier) (PRA-crd1) Hundebesitzer When breeding with merle dogsMost of canine retinal diseases with known causal mutations are rod cone degenerations also known as progressive retinal atrophies (PRAs), which are characterized by progressive rod led photoreceptor degeneration that is followed by cone photoreceptor demise. In contrast, cone rod dystrophies are characterized by the relatively early loss of cone photoreceptors. Crd1 usually affects very young dogs (less than 1 year old) and causes severe photopic and
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