Leukoencephalomyelopathie (LEMP) - Rottweiler, Dogge CatCheck Mutation: DVL2 gene

Mutation: DVL2 gene

Die klinischen Anzeichen umfassen Belastungsintoleranz

and hematologic abnormalities

spontan auftretende

usually within the first few weeks of a puppy's life

Leukoencephalomyelopathie (LEMP) - Rottweiler, Dogge CatCheck Mutation: DVL2 geneCanine leukoencephalomyelopathy (LEMP) is a hereditary neurodegenerative disorder affecting the white matter of the central nervous system. The disorder is characterized with myelin degradation in the white matter of the brain and spinal cord. Affected dogs show symptoms of weakness, incoordination of voluntary movements (ataxia), abnormal (hypermetric) gait, dragging of paws and loss of conscious proprioception, the sense of body position and